Seneca Vacation Rentals - HolidayHomes base64Hash Seneca Vacation Rentals - HolidayHomes

Seneca Vacation Rentals

Browse 273 available vacation homes and compared across 9 trusted partners

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Top-Rated Vacation rentals in Seneca

Book the highest-rated Seneca vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

House Seneca
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
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House Seneca
House with yard, patio & barbeque | Lake view
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House Seneca
Summer weeks are booking FAST! Get yours booked today!
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House Seneca
500 FT OF DEEP WATER FRONTAGE ON THE BEAUTIFUL EMRALD COLOR WATER OF LAKE KEOWEE
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House Seneca
Spacious Log Cabin on Point Lot, Private Beach, Boat and PWC Rental Available
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House Seneca
Keowee Adventures Peaceful Lakefront Home on Keowee 7 Miles from Clemson!
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House Seneca
Vacation home with terrace, garden & barbecue | Lake view
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House Seneca
Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson
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House Seneca
New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
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Condo Seneca
Lake Keowee Condo with Great Views! Near Clemson, Marina, Hiking, Waterfalls!
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House Seneca
Family-friendly lovely house with BBQ, garden & patio | Lake view | Perfect for remote work | Pets are welcome
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House Seneca
Stunning Seneca Home w/ Lake Keowee Access!
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Cabin Seneca
Cozy cottage quiet and secluded but close to everything.
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House Seneca
Lakefront Treehouse Retreat Minutes from Clemson University!
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House Seneca
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
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Top 15 most Recommended Vacation Rentals in Seneca

Discover your ideal Seneca vacation rental with real-time comparisons of 273 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

House Seneca
House ∙ 6 guests ∙ 3 bedrooms

186 m² House

Seneca, Oconee County, South Carolina, United States
Charming house rental in Seneca for 6 guests featuring a cozy fireplace and stunning lakeview.
from $261
per night
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House Seneca
6 guests ∙ 3 bedrooms

House

Seneca, Oconee County, South Carolina, United States
This house rental in Utica accommodates 6 guests and features a cozy fireplace for a warm and inviting atmosphere.
from $148
per night
(3)
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House Seneca
House ∙ 8 guests ∙ 4 bedrooms

242 m² House

Seneca, Oconee County, South Carolina, United States
Spacious house rental in Seneca for 8 with a family-friendly kitchen and a beautiful lakeview yard.
from $365
per night
(172)
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House Seneca
12 guests ∙ 4 bedrooms

House

Seneca, Oconee County, South Carolina, United States
Spacious house rental in Seneca for 12 guests featuring a cozy fireplace and stunning lakeview.
from $544
per night
(28)
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Apartment Seneca
Apartment ∙ 6 guests ∙ 2 bedrooms

104 m² Apartment

Seneca, Oconee County, South Carolina, United States
This Seneca apartment rental accommodates 6 and features a family-friendly environment with a spacious kitchen.
from $203
per night
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Cabin Seneca
Cabin ∙ 6 guests ∙ 2 bedrooms

108 m² Cabin

Seneca, Oconee County, South Carolina, United States
This cozy cabin in Seneca accommodates 6 guests and features a family-friendly kitchen for all your cooking needs.
from $178
per night
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House Seneca
House ∙ 16 guests ∙ 5 bedrooms

372 m² House

Seneca, Oconee County, South Carolina, United States
Spacious house rental in Seneca for 16 features a cozy fireplace and offers stunning lakeview amenities for a perfect getaway.
from $674
per night
(128)
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House Seneca
8 guests ∙ 3 bedrooms

House

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 8 guests and features a cozy fireplace for a perfect family getaway.
from $333
per night
(93)
View deal
House Seneca
House ∙ 6 guests ∙ 3 bedrooms

130 m² House

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 6 guests and features a family-friendly yard for outdoor activities.
from $175
per night
(1)
View deal

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