Seneca Vacation Rentals - HolidayHomes base64Hash Seneca Vacation Rentals - HolidayHomes

Seneca Vacation Rentals

Browse 251 available vacation homes and compared across 8 trusted partners

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Top-Rated Vacation rentals in Seneca

Book the highest-rated Seneca vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

House Seneca
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
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House Seneca
Secluded Seneca/Clemson Lake Hartwell Waterfront, 3 miles to CU
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House Seneca
Located on beautiful Lake Keowee
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House Seneca
House with barbeque, garden & terrace | Lake view
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House Seneca
Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson
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House Seneca
Point Lot, Boat and PWC Rental
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House Seneca
Lakefront home with private beach & unbelievable sunsets on Lake Keowee
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House Seneca
Vacation home with terrace, grill & private pool | Lake view
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House Seneca
Beautiful lakefront home in quiet cove. Ask about discounted long-term rental.
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House Seneca
Keowee Adventures Peaceful Lakefront Home on Keowee 7 Miles from Clemson!
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House Seneca
New to VRBO! Big water views, private dock, pool table, 15 min Clemson!
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House Seneca
Children-friendly lovely vacation home with terrace & grill | Nature view
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House Seneca
Lakefront 4BR home with sandy beach and big views! Private Dock, 15min Clemson
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House Seneca
House with patio & barbeque | Lake view | Good for workation
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House Seneca
Lake Keowee: Lake front 7 mi from Clemson stadium
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Top 15 most Recommended Vacation Rentals in Seneca

Discover your ideal Seneca vacation rental with real-time comparisons of 251 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

House Seneca
House ∙ 6 guests ∙ 3 bedrooms

Vacation home with BBQ, patio & pool | Lake view

Seneca, Oconee County, South Carolina, United States
Charming house rental in Seneca for 6 guests featuring a cozy fireplace and stunning lakeview.
from $348
per night
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House Seneca
House ∙ 10 guests ∙ 4 bedrooms

Child-friendly wonderful house with barbeque & terrace

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 10 guests and features a cozy fireplace for a warm and inviting atmosphere.
from $428
per night
(20)
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House Seneca
House ∙ 12 guests ∙ 5 bedrooms

Child-friendly house with garden & barbeque | Lake view

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 12 guests and features a beautiful lakeview from the spacious balcony.
from $629
per night
(4)
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House Seneca
House ∙ 14 guests ∙ 4 bedrooms

Family-friendly lovely house with BBQ, garden & patio | Lake view | Perfect for remote work | Pets are welcome

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 14 guests and features a family-friendly kitchen with a beautiful lakeview.
from $535
per night
(44)
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House Seneca
House ∙ 10 guests ∙ 4 bedrooms

Family-oriented vacation home with private pool, terrace & hot tub | Dogs allowed

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 10 guests and features a private pool for a relaxing stay.
from $408
per night
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House Seneca
House ∙ 12 guests ∙ 5 bedrooms

Child-friendly vacation home

Seneca, Oconee County, South Carolina, United States
Spacious house rental in Seneca accommodates 12 guests and features a fully equipped kitchen for convenient meal preparation.
from $595
per night
(26)
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House Seneca
House ∙ 24 guests ∙ 7 bedrooms

House with grill & terrace | Lake view

Seneca, Oconee County, South Carolina, United States
This spacious house rental in Seneca accommodates 24 guests and features a beautiful balcony with stunning mountain views.
from $1,329
per night
(68)
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House Seneca
House ∙ 8 guests ∙ 4 bedrooms

Family-friendly vacation home with BBQ & garden

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 8 guests and features a cozy fireplace for a comfortable stay.
from $447
per night
(22)
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House Seneca
House ∙ 8 guests ∙ 3 bedrooms

Vacation home with garden & barbeque | Lake view

Seneca, Oconee County, South Carolina, United States
This house rental in Seneca accommodates 8 guests and features a beautiful lakeview for a relaxing getaway.
from $532
per night
(21)
View deal

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