Santee Vacation Rentals - HolidayHomes base64Hash Santee Vacation Rentals - HolidayHomes

Santee Vacation Rentals

Browse 303 available vacation homes and compared across 6 trusted partners

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Top-Rated Vacation rentals in Santee

Book the highest-rated Santee vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

Condo Santee
Waterfront Condo 3BR/3BA- Lake Marion, Ballards Point II, Santee, SC
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House Santee
House with garden, barbeque & terrace | Lake view | Perfect for remote work
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Condo Santee
Condo with terrace & pool | Lake view | Next to the beach
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Condo Santee
Sunsets on Lake Marion: 2BD Lakefront Luxury Bliss
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Condo Santee
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
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House Santee
House with pool
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House Santee
Vacation home with pool
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Condo Santee
Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95
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Condo Santee
Condo with hot tub, pool & barbeque
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Condo Santee
Condo with pool | Next to the beach
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Condo Santee
"Penthouse" on Lake Marion, SC at the Club Wyndham Resort 2 BR/2BA, Sleeps 8
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House Santee
Fully renovated 1959 lake front cottage. In-ground swimming pool and spa.
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Condo Santee
Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation
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Cabin Santee
CatDaddy Cabin - Lake Marion Cabin in Santee - lake view, fire pit, boat parking
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Condo Santee
Fully equipped condo with heated pool
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Top 15 most Recommended Vacation Rentals in Santee

Discover your ideal Santee vacation rental with real-time comparisons of 303 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

Condo Santee
Condo ∙ 12 guests ∙ 4 bedrooms

Children-friendly spacious condo with garden, pool & barbecue | Suitable for remote work

Santee, Orangeburg County, South Carolina, United States
This spacious condo in Orangeburg County accommodates 12 guests and features a relaxing pool for enjoyable gatherings.
from $326
per night
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Condo Santee
Condo ∙ 7 guests ∙ 3 bedrooms

Condo with pool, patio & yard | Lake view

Santee, Orangeburg County, South Carolina, United States
This spacious 7-person condo in Santee features a relaxing pool and is perfect for family-friendly gatherings.
from $276
per night
(1)
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Condo Santee
Condo ∙ 12 guests ∙ 4 bedrooms

Children-friendly condo with BBQ, garden & patio | Lake view | Suitable for remote work

Santee, Orangeburg County, South Carolina, United States
This spacious 12-capacity condo in Santee features a lovely balcony perfect for relaxing and enjoying the views.
from $406
per night
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Condo Santee
Condo ∙ 10 guests ∙ 3 bedrooms

Condo with heated pool

Santee, Orangeburg County, South Carolina, United States
This spacious condo in Santee accommodates 10 guests and features a balcony with stunning views.
from $292
per night
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Condo Santee
Condo ∙ 4 guests ∙ 2 bedrooms

Condo with 2 bedrooms for 4 persons

Santee, Orangeburg County, South Carolina, United States
This spacious condo in Santee accommodates 4 and features a family-friendly kitchen for convenient meal preparation.
from $229
per night
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Condo Santee
Condo ∙ 6 guests ∙ 2 bedrooms

Lovely condo with hot tub

Santee, Orangeburg County, South Carolina, United States
This cozy condo in Santee accommodates 6 guests and features a refreshing swimming pool for relaxation.
from $182
per night
(15)
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House Santee
House ∙ 6 guests ∙ 4 bedrooms

House with jacuzzi

Santee, Orangeburg County, South Carolina, United States
This house rental in Santee accommodates 6 guests and features a fully equipped kitchen for your convenience.
from $271
per night
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Condo Santee
Condo ∙ 8 guests ∙ 2 bedrooms

Fully equipped wonderful condo with pool, barbecue & jacuzzi | Lake view | Beach nearby | Pets are welcome

Santee, Orangeburg County, South Carolina, United States
This spacious 8-person condo in Santee features a private balcony with stunning views.
from $218
per night
(5)
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Condo Santee
Condo ∙ 20 guests ∙ 6 bedrooms

Children-friendly pleasant condo with garden, pool & BBQ | Lake view | Suitable for remote work

Santee, Orangeburg County, South Carolina, United States
This 20-capacity condo in Santee features a spacious balcony with stunning views and access to a community pool.
from $534
per night
(2)
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