Saint Charles Vacation Rentals - HolidayHomes base64Hash Saint Charles Vacation Rentals - HolidayHomes

Saint Charles Vacation Rentals

Browse 564 available vacation homes and compared across 7 trusted partners

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Top-Rated Vacation rentals in Saint Charles

Book the highest-rated Saint Charles vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

House Saint Charles
1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
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Apartment Saint Charles
Children-friendly rental apartment | City view
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House Saint Charles
Vacation home with yard | Nature view
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House Saint Charles
Vacation home | Nature view
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House Saint Charles
1920's Vintage Home in Historic Saint Charles - Fully Remodeled
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Apartment Saint Charles
Children-friendly rental apartment | City view
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House Saint Charles
House with garden & patio
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House Saint Charles
House with BBQ, garden & patio
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House Saint Charles
Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!
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Apartment Saint Charles
Rental apartment | City view
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House Saint Charles
House with patio, grill & garden
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House Saint Charles
Child-friendly lovely house with jacuzzi, patio & BBQ | Suitable for remote work | Dogs allowed
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Villa Saint Charles
Family-oriented villa
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Apartment Saint Charles
Lovely Couples Escape on Mississippi River!
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House Saint Charles
Children-friendly vacation home with patio & garden
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Top 15 most Recommended Vacation Rentals in Saint Charles

Discover your ideal Saint Charles vacation rental with real-time comparisons of 564 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

House Saint Charles
House ∙ 6 guests ∙ 2 bedrooms

House | Suitable for remote work

Saint Charles, St. Charles County, Missouri, United States
This house rental in Saint Charles accommodates 6 guests and features a fully equipped kitchen for your convenience.
from $302
per night
(24)
View deal
House Saint Charles
House ∙ 8 guests ∙ 4 bedrooms

Family-friendly pleasant vacation home with garden & patio | Good for workation

Saint Charles, St. Charles County, Missouri, United States
This house rental in New Town at St. Charles accommodates 8 guests and features a spacious yard for outdoor enjoyment.
from $185
per night
View deal
House Saint Charles
House ∙ 10 guests ∙ 4 bedrooms

Child-friendly house | Suitable for remote work | Pets allowed

Saint Charles, St. Charles County, Missouri, United States
This spacious house rental in Saint Charles accommodates 10 guests and features a fully equipped kitchen for family-friendly gatherings.
from $339
per night
(42)
View deal
House Saint Charles
House ∙ 10 guests ∙ 4 bedrooms

Family-oriented house with garden | Perfect for remote work

Saint Charles, St. Charles County, Missouri, United States
This spacious house rental in Saint Charles accommodates 10 guests and features a family-friendly yard for outdoor enjoyment.
from $598
per night
(25)
View deal
Apartment Saint Charles
Apartment ∙ 6 guests ∙ 2 bedrooms

Apartment | City view

Saint Charles, St. Charles County, Missouri, United States
Spacious apartment rental in Saint Charles accommodates 6 and features a modern kitchen for convenient living.
from $170
per night
(51)
View deal
House Saint Charles
House ∙ 6 guests ∙ 2 bedrooms

Family-oriented pleasant house with yard | Nature view | Perfect for remote work | Pet-friendly

Saint Charles, St. Charles County, Missouri, United States
This family-friendly house rental in Saint Charles accommodates 6 and features a cozy fireplace for added comfort.
from $127
per night
(81)
View deal
House Saint Charles
House ∙ 8 guests ∙ 2 bedrooms

Family-friendly house with garden & grill | Nature view | Perfect for remote work

Saint Charles, St. Charles County, Missouri, United States
This house rental in Saint Charles accommodates 8 guests and features a cozy fireplace for relaxing evenings.
from $148
per night
(13)
View deal
House Saint Charles
House ∙ 10 guests ∙ 4 bedrooms

Fully equipped charming vacation home with barbeque & patio | Nature view | Dogs allowed

Saint Charles, St. Charles County, Missouri, United States
Spacious house rental in Saint Charles for 10 guests featuring a fully equipped kitchen and pet-friendly accommodations.
from $195
per night
(31)
View deal
House Saint Charles
House ∙ 6 guests ∙ 2 bedrooms

Vacation home with yard, jacuzzi & patio | Dogs allowed

Saint Charles, St. Charles County, Missouri, United States
Charming house rental in Saint Charles for 6 guests featuring a spacious yard and pet-friendly accommodations.
from $169
per night
(5)
View deal

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