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Panama Vacation Rentals

Browse 15,523 available vacation homes and compared across 18 trusted partners

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Top-Rated Vacation rentals in Panama

Book the highest-rated Panama vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

House Punta Mala

Stunning 3 Bedroom Waterfront Villa with Infinity Pool

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House Rio Hato

STUNNING BEACHFRONT PROPERTY. CHARMING, PRIVATE, UNIQUE.

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Condo Panama Pacifico

Condo with grill, sauna & jacuzzi | Nature view

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Condo Rio Hato

Stunning Condo on a Swathe of Golden Sandy Beaches of Panama

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Villa Rio Hato

4 Bedroom Beach & Golf Detached Villa With Private Pool by Decameron

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House Boquete

Family-oriented vacation home with BBQ, yard & patio | Nature view | Perfect for remote work

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House Boquete

Children-friendly vacation home with hot tub, barbeque & heated pool | Pets allowed

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Condo Panama

Luxury Beachfront Condo with Amazing Ocean Views

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Condo Coloncito

Lovely condo with beach, mountain and pool view.

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Villa Bocas del Toro Province

Fully equipped beautiful villa with hot tub, private pool & patio | Nature view | Pets are welcome

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House Pribanco

House with barbeque, private pool & patio

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House Boca Chica

A entire beach house in front of the Pacific for nature-loving families!

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Apartment Villa Clara

Casa Piscina - House with a pool in David

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Apartment Santo Domingo

1st Floor Beach House Apartment just steps from the beach!

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House El Porvenir

Fully equipped charming house with yard, patio & private pool

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Top 15 most Recommended Vacation Rentals in Panama

Discover your ideal Panama vacation rental with real-time comparisons of 15,523 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

Apartment Panama City
Apartment ∙ 2 guests ∙ 1 bedroom

Children-friendly charming apartment with yard | Next to the beach

Panama City, Panama, Panama
Cozy apartment rental for 2 in Panama City featuring a charming balcony with city views.
from $44
per night
View deal
Apartment Panama City
Apartment ∙ 4 guests ∙ 2 bedrooms

Apartment with yard

Panama City, Panama, Panama
This apartment rental in Panama City accommodates 4 guests and features a family-friendly environment with a modern kitchen.
from $56
per night
View deal
Apartment Panama City
Apartment ∙ 4 guests ∙ 2 bedrooms

Family-friendly apartment with pool & garden | Close to the beach

Panama City, Panama, Panama
This spacious apartment rental in Panama City accommodates 4 and features a family-friendly kitchen for enjoyable home-cooked meals.
from $98
per night
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Apartment Panama City
Apartment ∙ 3 guests ∙ 1 bedroom

Rental apartment with pool

Panama City, Panama, Panama
This apartment rental in El Marañón accommodates 3 guests and features a family-friendly kitchen for convenient meal preparation.
from $77
per night
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Apartment Panama City
Apartment ∙ 2 guests ∙ 1 bedroom

Child-friendly apartment with yard | Beach nearby

Panama City, Panama, Panama
Cozy apartment rental in Panama City for 2 featuring a fully equipped kitchen perfect for your culinary adventures.
from $73
per night
View deal
House Villa Maria
House ∙ 6 guests ∙ 3 bedrooms

House with patio

Villa Maria, San Pablo Viejo Abajo, Panama
Charming house rental in Villa Maria accommodates 6 guests and features a family-friendly kitchen for your convenience.
from $27
per night
(1)
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Apartment Nueva Gorgona
Apartment ∙ 7 guests ∙ 3 bedrooms

Fully equipped apartment with pool & hot tub | Beach nearby | Dogs allowed

Nueva Gorgona, Chame, Panama
Spacious apartment rental in Nueva Gorgona for 7 guests featuring a relaxing pool.
from $52
per night
(1)
View deal
Condo Nueva Gorgona
Condo ∙ 4 guests ∙ 2 bedrooms

Children-friendly nice condo with garden, sauna & pool | Next to the beach

Nueva Gorgona, Chame, Panama
This cozy condo in Nueva Gorgona accommodates 4 guests and features a refreshing pool for relaxation and fun.
from $55
per night
(17)
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House Old Bank
House ∙ 4 guests ∙ 2 bedrooms

Beautiful vacation home with garden & terrace

Old Bank, Bastimento, Panama
This house rental in Old Bank accommodates 4 guests and features a spacious yard for outdoor relaxation.
from $102
per night
(5)
View deal

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