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Panama Vacation Rentals

Browse 15,055 available vacation homes and compared across 18 trusted partners

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Top-Rated Vacation rentals in Panama

Book the highest-rated Panama vacation rentals, rated by real guests for comfort, location, cleanliness, services and value for money

House Punta Mala
Stunning 3 Bedroom Waterfront Villa with Infinity Pool
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House Big Creek
Vacation home with yard, grill & patio
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House Rio Hato
STUNNING BEACHFRONT PROPERTY. CHARMING, PRIVATE, UNIQUE.
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House San Carlos District
Beach House with Ocean View - Rooftop Jacuzzi & Pool - Concierge Service
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House Cardenas
House with terrace, garden & private pool
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Condo Panama Pacifico
Condo with grill, sauna & jacuzzi | Nature view
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Condo Rio Hato
Stunning Condo on a Swathe of Golden Sandy Beaches of Panama
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House Coloncito
House with barbecue, garden & pool | Nature view
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House Playa Coronado
Fully Solar Beach Casita. Walk to Beautiful Coronado Beach! Enjoy the pool!
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Villa Rio Hato
4 Bedroom Beach & Golf Detached Villa With Private Pool by Decameron
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House Boquete
Children-friendly vacation home with hot tub, barbeque & heated pool | Pets allowed
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Condo Coloncito
Lovely condo with beach, mountain and pool view.
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Chalet Anton Valley
Bird Watchers Paradise. Villa San Antonio, Chalet, swimming pool BBQ terrace.
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House Pribanco
House with barbeque, private pool & patio
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Condo Punta Chame
Fully equipped beautiful condo with grill, garden & pool | Nature view
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Top 15 most Recommended Vacation Rentals in Panama

Discover your ideal Panama vacation rental with real-time comparisons of 15,055 properties, featuring recommended options based on the property location, value for money, and verified guest reviews.

Apartment Panama City
Apartment ∙ 3 guests ∙ 1 bedroom

Apartment | Perfect for remote work

Panama City, Panama, Panama
This family-friendly apartment rental in Panama City accommodates 3 and features a cozy fireplace for added comfort.
from $39
per night
View deal
House Villa Maria
House ∙ 6 guests ∙ 3 bedrooms

House with patio

Villa Maria, San Pablo Viejo Abajo, Panama
Charming house rental in Villa Maria accommodates 6 guests and features a family-friendly kitchen for your convenience.
from $27
per night
(1)
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Apartment Playa Coronado
Apartment ∙ 6 guests ∙ 1 bedroom

Family-oriented rental apartment with barbecue | Pets are welcome

Playa Coronado, Las Lajas, Panama
This apartment rental in Playa Coronado accommodates 6 guests and features a family-friendly kitchen for convenient meal preparation.
from $59
per night
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Cabin Altos del Maria
Cabin ∙ 2 guests ∙ 1 bedroom

Nice cottage with garden

Altos del Maria, Chame, Panama
This cozy cabin in Altos del Maria accommodates 2 guests and features a lovely yard for relaxation.
from $31
per night
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Apartment San Carlos
Apartment ∙ 3 guests ∙ 2 bedrooms

Apartment with pool & yard | Lake view

San Carlos, Panama, Panama
This San Carlos apartment rental accommodates 3 and features a refreshing pool for relaxation.
from $45
per night
(11)
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Condo Nueva Gorgona
Condo ∙ 4 guests ∙ 2 bedrooms

Children-friendly nice condo with garden, sauna & pool | Next to the beach

Nueva Gorgona, Chame, Panama
This cozy condo in Nueva Gorgona accommodates 4 guests and features a refreshing pool for relaxation and fun.
from $54
per night
(15)
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Apartment Santo Domingo
Apartment ∙ 6 guests ∙ 2 bedrooms

Rental apartment with barbecue, yard & patio

Santo Domingo, Las Tablas, Panama
Spacious apartment rental for 6 in Santo Domingo featuring a family-friendly kitchen and convenient parking.
from $34
per night
(9)
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Cabin Playa Coronado
Cabin ∙ 4 guests ∙ 2 bedrooms

Pleasant cottage with grill, hot tub & private pool | Pet-friendly

Playa Coronado, Las Lajas, Panama
This cozy cabin in Playa Coronado accommodates 4 guests and features a private pool for relaxation and fun.
from $75
per night
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House Old Bank
House ∙ 4 guests ∙ 2 bedrooms

Beautiful vacation home with garden & terrace

Old Bank, Bastimento, Panama
This house rental in Old Bank accommodates 4 guests and features a spacious yard for outdoor relaxation.
from $102
per night
(5)
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